All Articles

Editorial Commentary 
The dry retina paradox: interpreting MERLIN in clinical practice
Lasse J. Cehofski, Yousif Subhi
AME Clinical Trials Review  
2026;
4:
31
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Editorial Commentary 
Androgen deprivation therapy and definitive radiotherapy for intact prostate cancer in the modern era: personalized medicine on the horizon
Joshua R. Niska, Nathan Y. Yu, Jean-Claude M. Rwigema, Sarah E. James, Brady S. Laughlin, Carlos E. Vargas, Steven E. Schild
AME Clinical Trials Review  
2026;
4:
29
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Editorial Commentary 
We will not have to wait—building regulatory confidence in early endpoints for high-risk breast cancer
Keli Santos-Parker, Laura Esserman
AME Clinical Trials Review  
2026;
4:
28
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Editorial Commentary 
Precision in practice: a new standard in early-relapsing HR+ breast cancer
Nathalie LeVasseur, Karen A. Gelmon
AME Clinical Trials Review  
2026;
4:
27
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Editorial Commentary 
Less is more: lessons from adding antiangiogenesis to 1L chemo-immunotherapy in non-small cell lung cancer (LEAP-006)
Federico Monaca, Igor Gómez-Randulfe, Raffaele Califano
AME Clinical Trials Review  
2026;
4:
26
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Editorial Commentary 
EPIK-O and beyond: PI3Kα inhibition plus PARP blockade in platinum-resistant BRCA-wildtype ovarian cancer
Mali Barbi, Divya Bhana, Veena S. John
AME Clinical Trials Review  
2026;
4:
25
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Editorial Commentary 
Neoadjuvant osimertinib: a new standard in resectable EGFR-mutated non-small cell lung cancer?
Takahiro Karasaki
AME Clinical Trials Review  
2026;
4:
24
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Editorial Commentary 
Where are we LEAPing with anti-angiogenics and immunotherapy combinations?—reflections from the LEAP-008 study
Alessandra Merlini, Paolo Bironzo
AME Clinical Trials Review  
2026;
4:
23
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Editorial Commentary 
Extensive-stage small cell lung cancer: progress, slowly but surely
Ojbindra KC, Apar Kishor Ganti
AME Clinical Trials Review  
2026;
4:
22
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Letter to the Editor 
Reply to: Ibrutinib plus venetoclax for patients with relapsed or refractory mantle cell lymphoma: an editorial on the phase 3 SYMPATICO trial
Michael Wang, Jutta K. Neuenburg, Constantine S. Tam
AME Clinical Trials Review  
2026;
4:
21
.
Letter to the Editor 
Response to “Steroid-Limited Isatuximab-Based Quadruplet Therapy in Elderly, Transplant-Ineligible Multiple Myeloma: A REST Trial Commentary”
Frida Bugge Askeland, Fredrik Schjesvold
AME Clinical Trials Review  
2026;
4:
20
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Editorial Commentary 
Revisiting CDK4/6 inhibition and SERDs: EMBER-3 and the path forward
Carlos Henrique Barrios, Tomás Reinert
AME Clinical Trials Review  
2026;
4:
19
.
Editorial Commentary 
Reframing the immunotherapy landscape in borderline resectable pancreatic ductal adenocarcinoma: progress or plateau?
Alice Cattelani, Isabella Frigerio
AME Clinical Trials Review  
2026;
4:
18
.
Editorial Commentary 
Current and around-the-corner therapies in platinum-resistant ovarian cancer: an insight into the ROSELLA study
Valentina Tuninetti, Giorgio Valabrega
AME Clinical Trials Review  
2026;
4:
17
.
Editorial Commentary 
Cachexia, cytokines, and caution: lessons from tocilizumab in advanced pancreatic ductal adenocarcinoma
Carolyn Moloney-Lineen, Devalingam Mahalingam
AME Clinical Trials Review  
2026;
4:
16
.
Editorial Commentary 
Not so fast—should neoadjuvant chemotherapy be routine in resectable pancreatic cancers?
Coyin Oh, Devalingam Mahalingam
AME Clinical Trials Review  
2026;
4:
14
.
Review Article 
A literature review and reflection on clinical trials: current challenges, future directions, and potential strategies to overcome practical barriers
Kaiping Zhang, Savvas Lampridis, Charles B. Simone II, Ionut Negoi, Yan Peng, Binghan Shang, Yao Lin, Yaling Cheng, Fanghui Yang, Vishal G. Shelat, Kamyar Kalantar-Zadeh
AME Clinical Trials Review  
2026;
4:
12
.
Letter to the Editor 
Reply to: Xaluritamig: a first step towards a new target, new mechanism for metastatic prostate cancer
Kevin K. Zarrabi, Wm. Kevin Kelly
AME Clinical Trials Review  
2026;
4:
11
.
Editorial Commentary 
Chimeric antigen receptor T cell therapy in prostate cancer: racing to prime time
Margaux E. Wooster, Mark N. Stein
AME Clinical Trials Review  
2026;
4:
10
.
Editorial Commentary 
Long-term clopidogrel for secondary prevention—towards resolution of complex problem?
Akshyaya Pradhan, Monika Bhandari
AME Clinical Trials Review  
2026;
4:
9
.
Editorial Commentary 
Encorafenib, cetuximab and chemotherapy: a mole against BRAF mutant metastatic colorectal cancer
Benoist Chibaudel
AME Clinical Trials Review  
2026;
4:
8
.
Editorial Commentary 
Ibrutinib’s role in early-stage chronic lymphocytic leukemia: delayed progression but no survival advantage
Kelly Meza, Jacqueline C. Barrientos
AME Clinical Trials Review  
2026;
4:
7
.
Editorial Commentary 
Asciminib: a revolution in the tyrosine kinase inhibitors era
Mario Annunziata, Fabio Stagno
AME Clinical Trials Review  
2026;
4:
6
.
Editorial Commentary 
The role of lisocabtagene maraleucel for relapsed/refractory follicular lymphoma: a commentary
Abigail T. Huetteman, Julio C. Chavez
AME Clinical Trials Review  
2026;
4:
5
.
Review Article 
From the PACIFIC to the ADRIATIC: a literature review of 38 years of failed maintenance trials in small cell lung cancer post-chemoradiation
Alexandria Lee, Misako Nagasaka, Sai-Hong Ignatius Ou, Zhaohui Liao Arter
AME Clinical Trials Review  
2026;
4:
4
.
Review Article 
Clinical advancements in total neoadjuvant therapy for locally advanced rectal cancer: a narrative review
Angelo Pirozzi, Celine Hoyek, Naohiro Okano, Leticia Assad Maia Sandoval, Binbin Zheng-Lin, Oluseyi Abidoye, Cody Eslinger, Mohamad Bassam Sonbol, Mitesh J. Borad, Tanios S. Bekaii-Saab
AME Clinical Trials Review  
2026;
4:
3
.
Review Article 
The role of minimal residual disease measurement in multiple myeloma
Bhavesh Mohan Lal, Nikhil Vojjala, Nikhila Sampath Kumar, Carolina Schinke
AME Clinical Trials Review  
2026;
4:
2
.